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Awareness, Health and the Possibility of a New Tool
The male fertility crisis is real — and it’s growing. Over the past decades, studies have shown a significant global decline in sperm quality. This isn’t just a fertility issue — it’s a broader health concern. Sperm quality reflects much more than the ability to conceive; it can provide valuable insights into a man’s overall health, from hormonal balance and metabolism to cardiovascular and mental well-being.
That’s why it’s essential for men to check their sperm health, even before trying to start a family. Early awareness can help identify underlying health issues, promote preventive care, and support healthier lifestyles.
It’s time to talk openly about men’s fertility and make it a normal part of health conversations. Breaking the stigma empowers men to take control of their reproductive and general health.
We’re pushing the boundaries of reproductive science — because innovation starts with curiosity.
We’re developing innovative tools to assess sperm health — going beyond traditional fertility tests — to better understand what sperm can tell us about men’s bodies and overall well-being.
Advancing these new methods is a vital step toward improving both fertility diagnosis and men’s long-term health.
What makes it exciting:
Molecular Fingerprint Detection – Instead of simply observing sperm under a microscope, we analyze unique biochemical “fingerprints.”
Objective Quality Markers – By studying proteins, lipids, and DNA components, we can detect subtle changes that conventional tests often miss.
Fast & Informative – Designed to deliver clear, data-driven insights into sperm and overall health once fully validated.
Current Methods of Semen Assessment
Semen consists of two primary components: sperm cells and seminal fluid.
A semen analysis evaluates both the physical and cellular characteristics of a sample. Physical assessments include measurements of color, odor, pH, viscosity, and liquefaction time, while cellular evaluations focus on parameters such as volume, sperm concentration, morphology, motility, and progressive movement.
To ensure accuracy and account for natural variation, semen analyses are usually performed multiple times over separate intervals.
Although conventional semen analysis methods are widely used, their moderate sensitivity and specificity limit overall diagnostic accuracy.
This highlights the need for new, standardized, and highly sensitive techniques that can provide more precise assessments of semen quality — both in clinical laboratories and at-home testing environments (2).
Men today produce significantly fewer sperm than previous generations — and the decline is accelerating. Global meta-analyses report a drop of more than 50% in sperm counts since the 1970s, revealing a consistent and alarming trend across continents (1).
From Europe and North America to Asia and Africa, research points in the same direction: modern men are producing fewer sperm, with reduced motility and higher rates of abnormal morphology compared to their fathers and grandfathers. This rapid decline not only raises concerns about fertility but also underscores broader implications for male reproductive and overall health.
What’s Causing It?
The decline in sperm quality is linked to a complex mix of modern lifestyle and environmental factors. Endocrine-disrupting chemicals (EDCs), found in plastics, cosmetics, and even receipts, can mimic hormones and interfere with sperm production. Sedentary lifestyles and obesity contribute by lowering testosterone levels and increasing oxidative stress. Everyday habits such as chronic stress, poor sleep, and consumption of processed foods further undermine reproductive health. On top of this, pollution and microplastics pose emerging risks, with recent studies even detecting microplastics in human testicular tissue.
Low sperm count isn’t only about the ability to conceive — it’s also a marker of overall male health. Men with poor sperm quality are statistically more likely to develop metabolic, cardiovascular, and even cognitive diseases later in life. Sperm, it turns out, is like the “canary in the coal mine” for male wellbeing (3) (4).
It's Why There Is a Need for Proper Diagnosis
A clear understanding of sperm quality can serve as an early warning—not just for fertility issues, but also for overall health.
Sperm analysis can reveal certain underlying medical conditions, such as hormonal imbalances or metabolic problems, that might otherwise go unnoticed. Moreover, knowing sperm health can motivate men to adopt healthier lifestyle choices—improving diet, exercising more and regularly, and avoiding harmful habits. It can can enhance both reproductive and general health, ultimately increasing the chances of successfully becoming a parent.
Help us nail down a fresh approach to checking out male fertility!
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Reference:
1.Kimmins S, Tuffnell D, Smith J. What’s really behind the male infertility crisis? New study seeks answers. Nat Rev Urol. 2023. Available from: https://www.news-medical.net/news/20231015/Whats-really-behind-the-male-infertility-crisis-New-study-seeks-answers.aspx
2.Tanga BM, Qamar AY, Raza S, Bang S, Fang X, Yoon K, Cho J. Semen evaluation: Methodological advancements in sperm quality-specific fertility assessment — A review. Anim Biosci. 2021;34(8):1253–70. https://doi.org/10.5713/ab.21.0072.
3.Eisenberg ML, Li S, Cullen MR, Baker LC. Increased risk of incident chronic medical conditions in infertile men: analysis of United States claims data. Fertil Steril. 2016;105:629–636. doi: 10.1016/j.fertnstert.2015.11.011. [DOI] [PubMed] [Google Scholar][Ref list]
4.L Priskorn, R Lindahl-Jacobsen, T K Jensen, S A Holmboe, L S Hansen, M Kriegbaum, B S Lind, V Siersma, C L Andersen, N Jørgensen, Semen quality and lifespan: a study of 78 284 men followed for up to 50 years, Human Reproduction, Volume 40, Issue 4, April 2025, Pages 730–738, https://doi.org/10.1093/humrep/deaf023